One study showed that moxibustion can alleviate low-grade gastrointestinal inflammation in postinfectious/postinflammatory IBS (PI-IBS) and relieve visceral hypersensitivity by regulating intestinal microorganisms and controlling NLRP6 inflammatory small body signal conduction, thus controlling gastrointestinal inflammation and regulating gastrointestinal movement [12]. Here, NLRP6 is linked to irritable bowel syndrome.