In bladder cancer, exosome-transmitted lncRNA PTENP1 was reported to suppress bladder cancer progression by competitively binding to microRNA-17 [16], exosomal lncRNA LNMAT2 illustrated to promote lymphatic metastasis in bladder cancer [17], and hypoxic exosomes were found to facilitate bladder tumor growth and development through transferring lncRNA UCA1 [18]. This evidence concerns the gene LINC00858 and urinary bladder carcinoma.