Mutations in troponin C (Slow skeletal troponin C,Cardiac troponin C,TNNC1) mainly cause hypertrophic cardiomyopathy (HCM), and the effect of this gene on skeletal muscle function has not been investigated, and it is also by possible that the skeletal muscle function induced by this gene is disorders are considered to be one of the symptoms of HCM (43). Here, TNNC1 is linked to hypertrophic cardiomyopathy.