In cases of glioblastoma, there is a protein called isocitrate dehydrogenase (IDH), which, according to the latest WHO CNS 5 classification, there is no IDH-mutant glioblastoma, only IDH-wildtype glioblastoma or IDH-mutant astrocytoma. The gene discussed is IDH3A; the disease is astrocytoma (excluding glioblastoma).