Compared with the more aggressive diffuse large B-cell lymphoma (DLBCL), SMZL genomes infrequently harbour balanced chromosomal translocations, though IgH locus translocations can occur (9% of cases) in t(14;19)(q32;q13), t(6;14)(p21;q32), t(9;14)(p13;q32), and t(1;14)(q21;q32), targeting BCL3, CCND3, PAX5, and BCL9, respectively [39, 85]. Here, BCL9 is linked to diffuse large B-cell lymphoma.