Specifically, 13 CpG sites exhibited strong colocalization with T2DM, including ACSL1 (cg03977443), COQ4 (cg14458731), COX19 (cg22301154), DHRS4 (cg20021513), DNAJC11 (cg01053213, cg24361350), GCDH (cg17414007, cg21050076), ISCA2 (cg16374328), MTFMT (cg25698089), SLC25A16 (cg01284033), TRUB2 (cg14458731), and TUFM (cg00348858). The gene discussed is TUFM; the disease is type 2 diabetes mellitus.