Sex, smoking history, drinking history, coronary artery disease, neuropathy, PVD, retinopathy, nephropathy, BMI, duration of diabetes, TC, FBG, HDL-C, LDL-C, hs-CRP, and Ua factors were more homogeneous (I2<50%); thus, a fixed-effects model was applied. This evidence concerns the gene CRP and diabetes mellitus.