TMEM127 and hereditary leiomyomatosis and renal cell cancer: In recent years, germline TMEM127 mutation–related familial PPGL; fumarate hydratase (FH) mutation–related hereditary leiomyomatosis and renal cell carcinoma syndrome (HLRCC); and MYC-associated factor X (MAX) mutation–related multiple endocrine tumors, including PPGL, have been discovered and reported (1–10).