ERBB2 and cancer: Zhao et al. discovered that m1A regulatory gene in digestive tract cancer was relevant to the occurrence of cancer by modulating ErbB2 and mTOR [28].Other studies revealed that APA was relevant to NSCLC, and cleavage stimulation factor subunit 2 (CSTF2) may regulate 3′UTR length to serve as an oncogene in NSCLC [29].