RNase A is a ribonuclease with potent cytotoxicity, which can degrade a variety of RNA molecules in tumor cells and eventually cause cell apoptosis.[38] To visually demonstrate the effect of protein delivery, Western Blot (WB) was used to examine the level of intracellular RNase A (Figure S13a, Supporting Information). This evidence concerns the gene RNASE1 and neoplasm.