CTAG1B and neoplasm: Additionally, preclinical studies have consistently demonstrated that epigenetic drugs demethylation such as decitabine (5‐aza‐2′‐deoxycytidine, DAC) led to increased NY‐ESO‐1 expression specifically in tumour cells, which stimulated specific immune responses and resulted in reduced tumour burden and prolonged survival in several mouse models.19, 20, 21