Researchers have demonstrated the anti-inflammatory role of PLB in neurodegenerative diseases such as Parkinson’s disease, where PLB could effectively provide neuroprotection to PD mice models by inhibiting inflammation via the TLR/NF-κB pathway and reduced expression of IL-1β, TNF-α, and IL-6 mRNA levels [19]. This evidence concerns the gene NFKB1 and Parkinson disease.