We further evaluated the apoptotic role of TXNDC5 in the anti-cancer effect of parecoxib and resveratrol, the TXNDC5 vector-transfected DLD-1 cells and empty vector-transfected cells were treated with parecoxib and resveratrol combination, and then we assessed the expression of cleaved PARP and Bax by Western blotting. Here, TXNDC5 is linked to cancer.