TNF and coronary artery disorder: However, in the CHD-48-LP group, there was a noteworthy decrease in TNF-α and IL-6 expression (1.27 ± 0.89, 1.69 ± 0.51, respectively) compared to the CHD-48 group (p < 0.05, 4.38 ± 0.83, 4.27 ± 1.89, respectively).