NRF1 and steatosis: ↓ The hepatic TC, TC, L-LDL, ALT, and AST levels;↓ The hepatic steatosis and inflammatory infiltration;↓ The generation of hepatic malondialdehyde (MDA);↓ The hepatic ROS levels;Protection against hepatic oxidative stress; ↓ pAMPKα, PGC-1α, and SIRT3 proteins in liver;↑ ERRα, Nrf-1, and Nrf-2 genes in liver.