IAPP and type 2 diabetes mellitus: In our previous studies, the O-BN diet increased satiety and improved gastrointestinal (GI) symptoms, as well as reduced the body mass index (BMI) and levels of metabolic (e.g., glucose, islet amyloid polypeptide (IAPP)) and inflammatory (e.g., IL-18) markers in T2D patients following the diet for 3 months [30,33].