CAT and Hepatic fibrosis: Such effects were observed in rats with liver fibrosis induced by thioacetamide (inhibiting liver fibrosis progression, reducing proliferating cell nuclear antigen PCNA, preventing hepatocyte oxidation, increasing superoxide dismutase SOD activity, catalase CAT, decreasing malondialdehyde MDA, and reducing liver cell inflammation) [63] and in rats intoxicated with cyclophosphamide (mildly enlarged portal vein, mild periportal mononuclear cell infiltration, periportal and portal collagen fibre formation) [77].