For example, fucosylated clusterin (CLU), a glycoprotein known as apolipoprotein J (APOJ), implicated in apoptosis, cell cycle regulation and DNA repair [199], represents a luminal BC-associated glycoform that can play a role in BC progression via pro-angiogenic cytokines and TNF-α production by intratumoral macrophages [200]. This evidence concerns the gene TNF and breast cancer.