The GnRH agonists, triptorelin, decapeptyl GnRH and goserelin, exerted cytotoxic effects on ovarian or endometrial cancer cells, whereas the growth rate of prostate cancer cells was decreased by both leuprolide and triptorelin [22,25,30,31,65,66,67]. The gene discussed is GNRH1; the disease is Familial prostate cancer.