CTSB and oral lichen planus: Other markers for the early detection of the malignant transformation of OLP into OSCC include Intercellular Adhesion Proteins, Cell Cycle Regulators, Apoptotic Biomarkers, which include proteins such as p53, p63, p73, and others, Tissue Remodeling Factors, enzymes such as matrix metalloproteinases (MMPs) and cathepsin B (CB), Inflammatory Mediators, Growth Factor Receptors, and Hormonal Receptors.