In addition to the importance of known mutations, such as changes in the fibrillin 1 gene (FBN1) in Marfan syndrome, which have already been described in association with connective tissue diseases [8,15], other genes have also been recognized as relevant to the disease-causing process and investigated in greater depth, expanding knowledge about the variety of possible genetic triggers [4,9,16,17,18,19]. This evidence concerns the gene FBN1 and connective tissue disorder.