PSTPIP1 and Pyoderma gangrenosum-acne-suppurative hidradenitis syndrome: Despite the fact that PASH syndrome pathophysiology is still unclear, mutations in the coding region of PSTPIP1 have been identified [56], and an increased number of CCTG repeats in the PSTPIP1 promoter region appears to be a consistent finding in PASH patients, governing a complex network of interactions between innate and adaptive immunity and environmental factors [54].