ADAMTS13 and myocardial infarction: Myocardial ischaemia/infarction is a major cause of global morbidity and mortality; a meta-analysis of >3500 participants (with myocardial infarction and healthy controls) showed that ADAMTS13 level below the 5th centile was associated with a moderate increased risk of myocardial infarction (OR 1.89, [95% CI 1.15–3.12]) [32].