Those with cognitive impairment were more likely to be men (p = 0.021), aged 75 and over (p < 0.001), underweight (p = 0.018), with a history of stroke (p = 0.019), a prealbumin level < 0.20 g/L (p = 0.003) and other findings of undernutrition, had at least three comorbid chronic conditions (p = 0.015) and were less likely to be obese (p = 0.006). The gene discussed is TTR; the disease is Stroke.