FOLH1 and posterior cortical atrophy: Sommer et al. studied the effects of manipulating AR activity on PSMA expression in two castration-sensitive PCa cell lines with non-detectable PSA protein level (LAPC4) and average PSMA protein level (LNCaP), as well as in the LNCaP sub-cell line C4-2, representing a castration-resistant cell model with high PSMA expression [41].