The search was performed on Pubmed using the search terms “prostate-specific membrane antigen”, “PSMA”, ”FOLH1”, “glutamate carboxypeptidase II”, or “folate hydrolase” in conjunction with “prostate cancer” or “prostate carcinoma”, as well as one of the following terms: “biology”, “expression”, “progression”, “signaling”, “epigenetic”, “androgen”, “folate”, “homodimer”, or “dimerization”. The gene discussed is FOLH1; the disease is prostate cancer.