This has been linked to cytokine activity, including TNF-α, interleukin-6 (IL-6), and interleukin-12 (IL-12) family (IL-12, IL-27, IL-23, IL-35, and IL-39), pointing to their crucial role in the inflammatory response and T1D development [7,9,10,11,12,13,14,15,16,17]. Here, TNF is linked to type 1 diabetes mellitus.