Another recent article reported association of GD with pemphigus foliaceus observed in the case of a 63-year-old woman with a recurrent BCC on the right lower eyelid with infiltration of the orbital floor and compromise of the rectus and inferior oblique muscles, treated with an antagonist of the smoothened receptor (SMO) that inhibits the Hedgehog signaling pathway and extensive surgery. Here, SMO is linked to pemphigus foliaceus.