TNF and anxiety disorder: In individuals with current depressive or anxiety disorders compared to healthy controls, elevated levels were observed in CRP, IL-6, IL-8, IL-18, MCP-1, MIP-1α, MIP-1β, MMP2, and TNF-β, while TNF-α, IL-10, IFN-γ, IL-2, and IL-4 levels either showed no significant elevation or were lower.