Chen et al. conducted a comprehensive pan-cancer analysis, examining the prevalence of Kelch-like ECH-associated protein 1 (KEAP1) mutations in a cohort of 40,167 patients with various cancer types (including lung cancer, endometrial cancer, hepatocellular carcinoma, head and neck cancer, bladder cancer, colorectal cancer, and esophagogastric cancer) using data from the cBioPortal online database [113]. The gene discussed is KEAP1; the disease is head and neck cancer.