However, due to the possibility of multiple organ dysfunction syndrome (MODS) development and a non-ubiquitous expression profile of the protein, combined with the presence of modifications affecting ACE2-RBD (receptor-binding domain of SARS-CoV-2 spike protein) interactions [4,5,6], attempts to find other potential receptors that could justify the events observed in the severe COVID-19 course have been undertaken. Here, ACE2 is linked to COVID-19.