EGFR and esophageal cancer: Molecular docking of the active compound 4c with the EGFR (PDB ID: 6DUK) and MetAP2 (PDB ID: 5D6E) proteins, which are potential targets in esophageal cancer, revealed hydrogen bonding interactions between the functional groups of the compound, including the furan ring and carbonyl groups, with specific amino acid residues.