Strikingly, in our cohort, there was a pronounced inverse correlation between FLT3 mutations and ETV6-RUNX1, suggesting a mutually exclusive relationship between FLT3 mutation and ETV6-RUNX1 in ALL tumorigenesis, which may be attributed to the propensity of mutated patients to lack the fusion gene [27]. The gene discussed is ETV6; the disease is acute lymphoblastic leukemia.