IL6 and infection: In the case of IL-6 (the most important mediator of the inflammation, stimulating the synthesis of acute phase protein), we observed its increase after infection with L. europaeus of both genotypes (8-fold change, p = 0.003 for GI.1 vs. control and 6.8-fold change, p = 0.004 for GI.2 vs. control; Figure 5B).