However, during L. europaeus GI.1 infection we noted a downregulation of TRAF6 was a 2-fold reduction (p = 0.02) compared to the control, while during L. europaeus GI.2 genotype infection a downregulation of TRAF6 was 2.9-fold reduction (p = 0.005 vs. control) (Figure 2H). The gene discussed is TRAF6; the disease is infection.