However, Marutani et al. found that incubation of activated caspase 3 with 250 μM STS for 30 min reduced caspase 3 activity, and incubation of neuroblastoma cell lysates with STS using the same amount of time and concentration resulted in the persulfidation of caspase 3 [34]. The gene discussed is CASP3; the disease is neuroblastoma.