Again, significant associations between symptoms and other DE genes, different from SIK1, were no further pursued, as DE of the gene had not passed the test of significance (e.g., CX3CR1 in the ME/CFS co-diagnosed group or EGR2 in the FM subgroup not having received co-diagnosis of FM) (see Figure 6) or had shown lower correlation values (e.g., CX3CR1 with mental health of the SF-36 questionnaire) (Figure 8, upper left). Here, CX3CR1 is linked to myalgic encephalomeyelitis/chronic fatigue syndrome.