Significantly higher photodynamic activity in EGFR-sensitive cells pretreated with Ad-QRH *. Anticancer activity in cells without pretreatment indicates micelle degradation followed by Pc activation. Intravenous administration followed by intratumoral Ad-QRH * application increased tumor fluorescence intensity 5-fold, and NIR irradiation completely eradicated tumors. This evidence concerns the gene EGFR and neoplasm.