C3 and complement 3 glomerulopathy: A similar effect of pegcetacoplan on deposition of C3b fragments on relevant cells was described in a clinical trial of patients with the complement-mediated disorder of renal glomerulopathy C3G, where deposition of C3c fragments on renal glomeruli membranes was reduced at 12 and 52 weeks of pegcetacoplan treatment [70].