In these animals, miR-155-5p showed positive correlations with several genes, including Traf6, Cx3cl1, P2yr1, Nfia, Cxcr3, P2yr12, Arg1, and Mfn2, indicating a prominent role for this miRNA in regulating gene expression in both neurons and glial cells in the context of AD. This evidence concerns the gene ARG1 and Alzheimer disease.