Mueller et al. reported that the expression of specific serpin family members, including SerpinB2, SerpinE1, SerpinF2, and SerpinG1, are up-regulated in both the matched tissues (CRSwNP: middle turbinate polypoid mucosa; control: inferior turbinate) and NMDEs of patients with CRSwNP compared with their expression in the controls [57]. The gene discussed is SERPINF2; the disease is chronic rhinosinusitis with nasal polyps.