Six examples of common mutations in AML include FMS-like tyrosine kinase 3 (FLT3), nucleophosmin 1 (NPM1), CCAAT/enhancer binding protein alpha (CEBPA), runt-related transcription factor 1 (RUNX1), additional sex combs-like 1 (ASXL1), and tumor protein p53 (TP53) [41,43]. The gene discussed is NPM1; the disease is acute myeloid leukemia.