ADORA3 and hepatocellular carcinoma: For example, MRS1754, an A2B ADO receptor antagonist, has shown positive actions as an antifibrotic agent [58,217]; A438079, a P2X7R antagonist, promoted a reduction in inflammation and collagen accumulation [65]; 5-BDBD, a P2XR antagonist, alleviated liver fibrosis in an experimental model of methionine-choline deficient diet [78]; NF340, a P2Y11R antagonist, counteracted HCC cells [78,218]; CF102, an A3AR agonist, reduced HCC cell availability [219].