In the present study, the anti-Warburg mechanism of Ginsenoside F2 (GF2), a protopanaxadiol saponin compound derived from Panax ginseng [27], was explored in human cervical cancer cells in relation to glycolysis regulated by miR-139-5p and β-catenin/c-Myc signaling. The gene discussed is MYC; the disease is cervical carcinoma.