CX3CL1 and hepatocellular carcinoma: Chen et al. showed that CX3CL1 stimulates the chemotactic migration of CX3CR1+ NK cells through STAT3 signaling, and miR-561-5p promotes tumor growth and lung metastasis by suppressing CX3CL1 expression, leading to low NK cell infiltration and poor prognosis in patients with HCC [4].