The p.Leu39Ter variant in the PLN gene has also been found in a heterozygous state in a 61-year-old female patient with familial HCM and a clinical history of recurrent atrial fibrillation, palpitations, dyspnea, and presyncope and in large cohort studies of HCM patients [72,73,74]. This evidence concerns the gene PLN and atrial fibrillation.