-alleviated hepatic fibrogenesis by inhibiting the activation of HSCs and collagen deposition-↓ ALT, AST-displayed anti-inflammatory effects in CCl4-induced liver fibrosis-↓ IL-1β, IL-6-↓ the infiltration of CD68 and CD11b cells in liver-↓ γH2AX. Here, ITGAM is linked to Hepatic fibrosis.