COL1A1 and Hepatic fibrosis: -improved the pathological lesions of liver fibrosis-↓ serum ALT, AST, HYP, cholesterol, triglycerides-inhibited HSC activation-↓ the expressions of hepatic genes involved in liver fibrosis: LOX, TGF-β1, MCP-1, Col1α1, TIMP-1-attenuated liver oxidative stress through Nrf2 signaling pathway