Table 6 highlights how isoflavones mitigate liver fibrosis by reducing oxidative stress, inflammation, and collagen deposition, while inhibiting key fibrogenic pathways such as JAK2/STAT3, TGF-β/Smad, and ERK1/2 (calycosin, genistein, puerarin, glabridin, soy isoflavone, tectorigenin). The gene discussed is MAPK3; the disease is Hepatic fibrosis.