There are several diseases related to the LMNA gene presenting with adipose tissue dysfunction, such as Dunnigan disease or familial partial lipodystrophy type 2 (FPLD2), Hutchinson-Gilford progeria syndrome (HGPS), LMNA-associated atypical progeroid syndrome (APS) and mandibuloacral dysplasia type A (MADA) [7]. The gene discussed is LMNA; the disease is atypical Werner syndrome.