The correct processing of the A-type lamins is essential for the prevention of laminopathies, which are, as previously mentioned, caused by variants in the LMNA gene (such as Dunnigan disease or several premature ageing syndromes), in other genes that influence lamina processing (such as ZMPSTE24 gene variants in MADB or in restrictive dermopathy) or in genes that influence its proper functioning on chromatin (such as BANF1 gene variants in NGPS). This evidence concerns the gene LMNA and laminopathy.