Pro-inflammatory mediators, derived from de novo lipogenesis of MUFAs and PUFAs, fuel fatty acid oxidation in lipid scavenging receptors, including CD163 on tumour-associated macrophages (TAMs) [15], leading to polarisation in pro-tumoural M2 macrophages and continual immune modulation during tumour progression [16]. Here, CD163 is linked to neoplasm.