That RARβ may play a role in controlling the proliferation of PCa has been argued from the finding that stable transfection of RARβ into the RARβ-negative PC-3 cells led to increased sensitivity to the combined use of an RARβγ-selective agonist (SR11262) and a potent vitamin D3 analogue regarding the inhibition of clonal growth. Here, RARB is linked to posterior cortical atrophy.