FURIN and myocardial ischemia: Recently, evidence reported by Mazidi et al. from a nested case-cohort study of 3977 participants including 1976 IHD cases in the China Kadoorie Biobank (CKB) is supportive of an association between plasma furin protein levels and increased risk of incident IHD (HR = 1.236, SE = 0.062, FDR = 0.005 per SD increase in protein concentration) [4].