In women with PCOS, hyperandrogenism was evident from elevated levels of androstenedione (1.49 ± 0.59 ng/mL), DHEAS (152.8 ± 64.51 μg/dL), and free testosterone (median 1.34 pg/mL), as shown in Table 2, with clinical manifestations including acne (60%), facial hair (68%), and abdominal hair (60%). This evidence concerns the gene SULT2A1 and acne.